The different cannabinoids found on cannabis plant have different effects on the brain because of the endocannabinoid systems which consist of the receptors CB1 and CB2. The CB1 receptors are found on the parts of the brain that is a receptor that is responsible for emotions, cognition, and memory. If the CBD binds with CB1 receptors in the brain, since it does not have mind-altering properties then the mental and emotional functioning is enhanced through CBD.
There is some research that CBD positively impacts the brain to acts a lot of benefits without delivering side effects. The brain has natural properties to protect itself but with the use of CBD, the brain functionalities are enhanced that the human body experience this enhancement in real time.
Neurological Effects of CBD
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Neuroprotective effects
CBD helps in the protection of neuron degeneration that is why it is a useful treatment for neurological diseases such as Alzheimer’s.
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Analgesic Effects
Treatment for chronic pain is the number 1 use of CBD in the medical field. Research shows that nonpsychoactive cannabinoids and CBD is used in all chronic pain treatment without causing any analgesic tolerance.
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Anti-tumor Effects
Even though CBD is in high doses, it does not contain toxic properties that affect the human body instead, it inhibits the growth of cancer cells from multiplying.
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Anti-anxiety Effects
The way CBD efficiently treat anxiety is that it has anti-paranoia properties that combat negative feelings to avoid being anxious.
How CBD Works In The Brain
CBD is able to deliver its effects through the molecular pathways in the* body. It may not directly bind with the cannabinoid receptors which are the CB1 and CB2 but it enhances the binding of different receptors throughout the body.
1.Serotonin System
This receptor is responsible for the CBD’s therapeutic properties. When CBD binds with the serotonin receptor, different hormones such as cortisol which is responsible for the reaction to stress and oxytocin which affects the social behavior aspects. When CBD releases these hormones, it will effectively affect a person’s mood, appetite, and cognition.
2.Vanilloid Receptors
When CBD binds with the TRPV1 receptor, vanilloid receptors will activate helping in the thermoregulation or temperature regulation that targeted inflammation and pain reception.
3.Orphan Receptor
When CBD interacts with GPR55 it will block its signaling to avoid the possible multiplication of the cancer cells. GPR55 is actually involved in the bone density and modulation of blood pressure but if it is overly active, it may respond negatively causing osteoporosis.
4.Nuclear Receptors
If CBD is bind with nuclear receptors or peroxisome proliferator it can produce anti-cancer effects.
How CBD Helps In The Brain Functioning
1.CBD reduces blood flow
The research found that there are CBD dominant strain that causes reduction of blood flow especially if the patient is experiencing mental and emotional illnesses such as anxiety and depression.
2.CBD reduces oxidative damage
The number cause of the brain’s malfunction or imbalance if there is oxidation stress that plays a major role in damaging the brain cells that may cause Parkinson’s disease and Alzheimer’s. The CBD minimizes the oxidative damage when it binds with the CB2 receptor.
3.CBD works to manage pain
The CBD is able to deliver its pain-killing properties when it binds with the CBD2 receptor. CBD blocks the message of pain to the brain by controlling the cellular functions to suppress inflammation that reduces the level of pain.
4.CBD has anti-psychotic properties
Anandamide is a neurotransmitter found in the body to play a major role in appetite, pain, depression, and memory. When CBD interacts with Anandamide, it has the ability to increase this neurotransmitter in the brain to help assist in managing pain, depression and appetite stimulation.
5.CBD as Anti-convulsant
The most common brain illness is a seizure. The use of CBD has been proven to reduce and gradually eliminates seizure. CBD has released its Anti-convulsant properties from the time CBD interacts with the receptors of the brain.
6.CBD promotes healthy brain cells
CBD doesn’t have negative effects on the mental functioning, it has been discovered that CBD helps in promoting neurogenesis that effectively serves as a buffer to avoid cognitive damage caused by aging, trauma and some memory disorders.
CBD has the ability to counteract on withdrawal symptoms because of addiction
CBD has the ability to disintegrate the connection of nicotine with the body. It has agents does not make you addicted to nicotine and opium and it effectively treats the withdrawal symptoms that will be experiencing.
Final Thoughts
Because of the promising effects of cannabis in the human body as well as in the medicinal field, more cannabis breeders are now focusing on producing more strains that produce high CBD levels. The use of CBD through oil, vaping, edibles, tinctures, topicals and capsules are the effective ways on how to greatly deliver the positive effects of CBD in the brain functioning.
